Review: The compositional variation of the rumen microbiome and its effect on host performance and methane emission

The rumen microbiome has the important task of supplying ruminants with most of their dietary requirements and is responsible for up to 90% of their metabolic needs.This tremendous feat is possible due to the large diversity of microorganisms in the rumen.The rumen is considered one of the most diverse ecosystems on the planet in terms of species d

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Progress towards the Elusive Mastitis Vaccines

Mastitis is a major problem in dairy farming.Vaccine prevention of mammary bacterial infections is of particular interest in helping to deal with this issue, all the more so as antibacterial drug inputs in dairy farms must be reduced.Unfortunately, the effectiveness of current vaccines is not satisfactory.In this review, we examine the possible rea

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Targeting treatment resistance: unveiling the potential of RNA methylation regulators and TG-101,209 in pan-cancer neoadjuvant therapy

Abstract Background Tumor recurrence and mortality rates remain challenging in cancer patients despite comprehensive treatment.Neoadjuvant chemotherapy and immunotherapy aim to eliminate residual tumor cells, reducing the risk of recurrence.However, drug resistance during neoadjuvant therapy is a significant hurdle.Recent studies suggest a correlat

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